13. Progression through the brain
Alzheimer’s Disease and the Brain
Plaques and tangles (shown in the blue-shaded areas) tend to spread through the cortex in a predictable pattern as Alzheimer’s disease progresses.
The rate of progression varies greatly. People with Alzheimer’s live an average of eight years, but some people may survive up to 20 years. The course of the disease depends in part on age at diagnosis and whether a person has other health conditions.
- Earliest Alzheimer’s – changes may begin 20 years or more before diagnosis.
- Mild to moderate Alzheimer stages – generally last from 2 – 10 years.
- Severe Alzheimer’s – may last from 1 – 5 years.
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